TY - RPRT AU - Riedmiller, Sebastian AU - Sutter, Matthias AU - Tonke, Sebastian TI - Designing Effective Interventions PY - 2025/Nov/ PB - Institute of Labor Economics (IZA) CY - Bonn T2 - IZA Discussion Paper IS - 18273 UR - https://www.iza.org/publications/dp18273 AB - We provide a systematic framework to diagnose underlying problems and predict intervention effectiveness ex-ante. For this, we developed a parsimonious and generalizable survey tool (anamnesis). Our anamnesis classifies underlying problems along three fundamental diagnoses: awareness, intention, and implementation problems. We validate the framework in an online experiment with 7,500 subjects. We find that (i) intervention effectiveness is heterogeneous across different settings, and (ii) our diagnosis accurately predicts this heterogeneity. On average, predicting a 10%-effect corresponds to an actual effectiveness of 8.92%. We further demonstrate the applicability of our framework to predict heterogeneities in the setting of COVID booster take-up. KW - context dependency KW - heterogeneous treatment effects KW - intervention design KW - experiment ER -