TY - RPRT AU - Haylock, Michael AU - Kampkötter, Patrick AU - Macis, Mario AU - Sauter, Jürgen AU - Seitz, Susanne AU - Slonim, Robert AU - Wiesen, Daniel AU - Schmidt, Alexander H. TI - Improving the Availability of Unrelated Stem Cell Donors: Evidence from a Major Donor Registry PY - 2022/Feb/ PB - Institute of Labor Economics (IZA) CY - Bonn T2 - IZA Discussion Paper IS - 15096 UR - https://www.iza.org/publications/dp15096 AB - The unavailability of potential stem cell donors poses a critical challenge for donor registries worldwide. This study investigates the impact of initiatives of a stem cell donor registry to enhance donors' availability for confirmatory typing. Initiatives ask donors to provide a sample for genetic analysis and/or information on their temporal unavailability. We analyzed 91,479 confirmatory typing requests from DKMS Germany, a large stem cell donor registry, exploiting a quasi-random initiative assignment based on observable characteristics. We find that, first, invitation to the initiatives increases donors' availability. Intention-to-treat estimates yield effects ranging from 2.5 to 3.2 percentage points, and local average treatment effects estimates range from 3.8 to 8.2 percentage points (baseline: 77.1%). Second, the difference in availability between participants and non-participants is over 10 percentage points. The initiatives yield a direct positive effect on donor availability and a selection effect through which participation signals a higher commitment. KW - intention-to-treat KW - sorting KW - registry initiatives KW - donor availability KW - unrelated stem cell donation KW - local average treatment effects ER -