TY  - RPRT
        AU  - Attanasio, Orazio
AU  - Conti, Gabriella
AU  - Jervis, Pamela
AU  - Meghir, Costas
AU  - Okbay, Aysu
        TI  - Gene x Environment Interactions: Polygenic Scores and the Impact of an Early Childhood Intervention in Colombia
        PY  - 2025/May/
        PB  - Institute of Labor Economics (IZA)
        CY  - Bonn
        T2  - IZA Discussion Paper
        IS  - 17897
        UR  - https://www.iza.org/index.php/publications/dp17897
        AB  - We evaluate impacts heterogeneity of an Early Childhood Intervention in Colombia, with respect to the Educational Attainment Polygenic Score (EA4 PGS) constructed from DNA data based on GWAS weights from a European population. We find that the EA4 PGS is predictive of several measures of child development, mother’s IQ and, to some extent, educational attainment. We also show that the impacts of the intervention are significantly greater in children with low PGS, to the point that the intervention eliminates the initial genetic disadvantage. Lastly, we find that children with high PGS attract more parental stimulation; however, the latter increases more strongly in children with low PGS.
        KW  - stimulation programs
KW  - early childhood development
KW  - GxE interactions
        ER  -